Researchers from IISER Pune have designed and synthesized new compounds that can release sulphur dioxide and slow the growth of Mycobacterium tuberculosis, the pathogenic bacterium causing tuberculosis. This work, published in the Journal of Medicinal Chemistry (55:553-557), presents a new candidate...

Cells come in different shapes and sizes, literally! Bacterial cells, for example, could be round, rod or even spiral in shape. What determines specificity in cell shape and what functional advantages could a cell have in assuming a certain shape and size? This intriguing aspect of life as we know i...

India Rising: Science in India; February 24, 2012. The IISERs featured in an article in Science. ...

A comprehensive study, the first of its kind in its in depth analysis, of CART (a neuropeptide with roles in appetite regulation) expression during different developmental stages of zebrafish has been recently reported by biologists at IISER Pune. A peptide that determines your appetite and a...

IISER Pune biologists have devised a simple system to count large number of small objects such as fruit flies (Drosophila) in the laboratory. This involves a set-up to scan anesthetized flies and a software, FlyCounter, to analyze the scanned image in order to count the flies. Experiments in ecol...

Srinivas Hotha leads a research group working on chemical glycosylation at IISER-Pune. Learn more about his research in this article. Srinivas Hotha obtained M.Sc. from the School of Chemistry at University of Hyderabad and a Ph.D. from Osmania University while working at the Indian Institute for...

Prof. Peter Schneider from the University of Muenster in Germany is one of the leading mathematicians working on p-adic methods in arithmetic and geometry. In recognition of his contributions to the field, he has been awarded the prestigious Leibniz Prize and the French-German Humboldt Prize. He was...

Arijit Bhattacharyay is an Assistant Professor in Physics and Biology at IISER Pune. His research interests are in the area of statistical physics and his work involves complex systems that have multiple degrees of freedom and generally not in equilibrium. Resistive regime of a superconductor repres...

Scientists at IISER-Pune have synthesized a new fluorescent ribonucleoside analog, which can slip in as a native nucleoside during transcription and report changes in RNA conformation via changes in fluorescence properties. Results on synthesis and characterization of this uridine analog have bee...

Structure and function of biomolecules are closely linked. Knowledge of structure can help predict and understand function, and information on function can be tremendously useful to repair or modulate the system for a desired output. One approach to understand structure-function relationship is t...